RNS System Webinar | Focal Epilepsy Treatment

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Educational Webinar – September 3, 2025, 6 pm PT

Is Long Term Seizure Reduction Possible?

Advanced Treatments for Focal Epilepsy Including the RNS® System

Register Here

Learn more about the RNS System and results from a landmark clinical study

Rapid Seizure Reduction

62%

Median seizure reduction at 6 months1

n=292

Long-Term Seizure Reduction

82%

Median seizure reduction at 3 years1

n=255

Seizure-Free Periods Achieved

42%

Of patients seizure free for 6+ months1,2

n=268

SUDEP Reduction

3x

Lower rate of SUDEP vs ASM placebo3

  1. RNS System Post-approval Study Oral Presentation, American Academy of Neurology, April 2025, all outcomes are ITT, median seizure reduction is observed case data
  2. At some point during the study
  3. Compared to placebo arm of ASM trial. 2.3/1000 patient years rate of SUDEP in RNS System prospective studies vs 6.9/1000 patient years rate of SUDEP in Anti-seizure Medication (ASM) placebo; Ryvlin et al, Lancet Neurol, 2011

Rx Only. The RNS® System is an adjunctive therapy for adults with refractory, partial onset seizures with no more than 2 epileptogenic foci. See important prescribing and safety information at www.NeuroPace.com/safety. Refer to the labeling for a description of the RNS® System and its components, indications for use, contraindications, warnings, cautions, adverse events and instructions for use.

Dr. Mark Krel

Featuring

Dr. Mark Krel

Mark Krel, D.O., is a proud native of Southern California. He completed his undergraduate, graduate, medical education, neurosurgical residency and fellowship training in California. After his neurosurgery residency, Dr. Krel received subspecialty training and served as a clinical instructor in stereotactic, functional, epilepsy, and pain neurosurgery at Stanford University. He specializes in epilepsy (including invasive monitoring, neuro-stimulation, and open and minimally invasive surgery), movement disorders, pain, and psychosurgery to treat depression, obsessive compulsive disorder and other diseases. Additionally, Dr. Krel has broad experience in general neurosurgery and trauma neurosurgery with training in California’s busiest Level I and Level II trauma centers.

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An epilepsy specialist, or epileptologist, is a neurologist who specializes in caring for people with epilepsy. They have completed an additional one or two years of subspecialty training in epilepsy care.
An epilepsy specialist, or epileptologist, is a neurologist who specializes in caring for people with epilepsy. They have completed an additional one or two years of subspecialty training in epilepsy care.
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Step 1 of 7

14%
    The RNS System is for individuals 18 and older who have focal epilepsy and have tried two or more medications without finding seizure control.

  • Based on your answers, your patient might benefit from the RNS System.

    Get your profile and a list of questions to ask your doctor.

  • Unfortunately it appears your patient is not an appropriate candidate for the RNS® System at this time.

  • The RNS® System is intended for patients who have undergone diagnostic testing that localized no more than 2 epileptogenic foci.

    If your patient has not undergone diagnostic testing, search here to find a comprehensive epilepsy center that can evaluate your patient, including determining if the RNS System is right for them.

  • If you are interested in learning more about the RNS® System, you can have an RNS® System professional contact you by filling out the form below:

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