The RNS® System —
Your Window to the Brain

The world’s first & only brain-responsive neurostimulation system

The RNS® System is an effective new treatment option for partial onset seizures. For the large number of adults who have failed medications, the RNS System treats seizures directly at their source – by stimulating the area of seizure onset.

The RNS System is the only device that can monitor and respond to your patient’s electrocorticographic activity over time, while they are engaged in normal daily activities. You personalize the device to detect patient-specific electrical patterns that can lead to a seizure. Within milliseconds of detecting these patterns, the device delivers imperceptible electrical pulses to the seizure source to normalize this activity — usually before seizure symptoms can occur.

 
 
 

To have the ability to look at an EEG over long periods of time, you're able to learn things about somebody's epilepsy that there's no other way to learn.

Dr. Vikram Rao, Epileptologist,University of California, San Francisco

Patients are tolerating these surgeries exceedingly well, and they're returning home to a much better quality of life.

Casey H. Halpern, MD, Assistant Professor of Neurosurgery, Stanford University

They don't know when they're getting the stimulation, so it's really painless.

Dr. David King-Stephens, MD, Epileptologist Sutter Pacific, Epilepsy Program, San Francisco

Life-changing clinical outcomes

NeuroPace is committed to the highest level of clinical science. The safety and efficacy of the RNS® System has been demonstrated in a large prospective, randomized, controlled, double-blinded pivotal trial and subsequent long-term study with follow-on data out to 9 years.

Effective seizure control

Patients treated with the RNS System experience significant seizure reductions that continue to improve over time, achieving 60% seizure reduction at three years and 66% seizure reduction at six years.1

1  Bergey GK, et al. Neurology, 2015

Improved quality of life

Patients treated with the RNS System reported statistically significant improvements in mood and overall quality of life, including physical health, mental health, cognition, and seizure worry.2

2  Meador KJ, et al. Epilepsy Behav, 2015

Favorable cognitive profile

Patients treated with the RNS System show no evidence of cognitive decline. In fact, they demonstrated statistically significant improvements in naming and verbal memory.3

3  Loring DW, et al. Epilepsia, 2015

Invisible and imperceptible

Once implanted and programmed, the RNS System is imperceptible to patients and invisible underneath their hair. It allows patients to focus on their lives, not their seizures.

Case Studies

The RNS® System is equally safe and effective in a variety of patients, including those with prior epilepsy surgery or prior vagus nerve stimulation. The device has been used to treat patients whose seizures originate in the mesial temporal lobe and in the neocortex. It has also been used to treat patients with unilateral and bilateral mesial temporal lobe onsets.

Occipital Lobe

Parietal Lobe

Periventricular Nodular Heterotopia (PVNH)

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