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Switch to RNS

Give your patients a new beginning when their VNS is due for replacement.

Now is the ideal time to consider the NeuroPace RNS System for your patients.

Get Started

Even with multiple medicines and the VNS, my epilepsy was out of control. I had lost my driver's license and was having up to seven seizures per day.

Josh, LIVING WITH RNS® SYSTEM since 2014
Read his story

Unmatched Seizure Control1-3

Rapid and long term seizure reduction was demonstrated in the largest FDA-reviewed prospective study in neuromodulation history for focal drug-resistant epilepsy (DRE).

View Publication

3 Year Median Seizure Reduction (%)

 
VNS
Study Group E01-E052 (n=93)
 
RNS® System
Post Approval Study1 (n=255)
 

Identifying RNS SYSTEM Candidates

Signs that the RNS System should be considered

  • Patients who have not achieved adequate seizure control on current therapy
  • Patient has a VNS battery nearing end-of-service
  • Patient frequently uses rescue medications or visits the ER
  • Patient experiences bothersome stimulation side effects
  • Accurate seizure tracking can be challenging with patient self-reporting alone

Why switch

Why Physicians Choose the RNS System

Get life-changing outcomes for your refractory patients

  • Life-Changing Outcomes

    In separate studies, the RNS System demonstrated 82%1 median seizure reduction at 3 years, compared to 44%2 reported with VNS therapy.

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  • Longest Battery Life

    Up to ~11 year battery life may mean less frequent replacement procedures.4

  • No Chronic Side Effects

    The RNS System is responsive. No chronic stimulation side effects like hoarseness, shortness of breath, or coughing.

  • Confident Care

    The RNS System provides simplified iEEG insights to help you confidently manage epilepsy care.

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  • Safe and Proven

    The RNS System is FDA-approved, supported by over a decade of real-world patient data, and proven to reduce seizures over the long term.

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  • Easy to Get Started

    NeuroPace offers guidance and support through the entire process.

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Easily get your patients started with The RNS® System

Whether you're evaluating your first candidate or you want to establish the RNS System as your standard of care, we are here to help.

Contact NeuroPace Find a Center

Note: Therapies were studied using different study designs. Caution must be exercised when comparing results.

  1. Eliashiv D et al, Neurology, 2026
  2. Morris et al, Neurology, 1999.
  3. Kaufmann et al., Epilepsia, 2024
  4. Median battery longevity of 10.8 years. Estimates for longevity were derived from medium stimulation utilization (mAh/day).

*Real person who volunteered to share RNS System experiences. Individual experiences may differ.

Rx Only. The RNS® System is an adjunctive therapy for adults with refractory, partial onset seizures with no more than 2 epileptogenic foci. See important prescribing and safety information at www.NeuroPace.com/safety. Refer to the labeling for a description of the RNS System and its components, indications for use, contraindications, warnings, cautions, adverse events and instructions for use.

© 2026 NeuroPace, Inc. All rights reserved. NeuroPace and RNS are registered trademarks of NeuroPace, Inc., Mountain View, CA

NP 260047 Rev1 / Rev Date 2026-04